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Using SynGO 35 to screen the DEPs in Akap11 -cKO mouse and AKAP11 -KO iNeuron, we found an enrichment in both pre- and postsynaptic compartments, sharing multiple sub-synaptic terms, including regulation of synapse assembly, SV exocytosis and endocytosis, postsynaptic membrane neurotransmitter receptor levels, and chemical synaptic transmission (Supplementary Fig

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Applications in Research As a molecular probe for studying short peptidemediated intracellular signalling Investigation of chromatin organisation, gene expression regulation, and telomere-associated processes in cell models In vitro studies examining peptidenucleus interactions and regulatory pathways As a reference compound in research involving pineal-derived peptide fragments Handling, Reconstitution & Stability Weigh under dry conditions

[Google Scholar] Pocernich C, Butterfield D

Neurology 91:e652e656 Nomura T, Inoue Y, Kagimura T, Nakashima K (2013) Clinical significance of REM sleep behavior disorder in Parkinsons disease