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Though patients often report good quality of life, symptoms such as fatigue, pain, pseudobulbar affect, depression, anxiety, thick secretions, and sialorrhea are reported frequently and contribute to worse quality of life [94,95,96]

In addition, to meet the requirements of SPPS, building blocks bearing specific protecting groups (such as Fmoc-Lys(Boc)-OH and Boc-Lys(Z)-OH) must be synthesized

These findings align with the idea that GPX4 is involved in sustaining the mitochondrial membrane potential under conditions of oxidative stress [224]

Methods: We conducted a systematic review and meta-analysis synthesizing randomized controlled trials (RCTs) which were retrieved by systematically searching: PubMed, EMBASE, Web of Science, SCOPUS, and Cochrane through March 27th, 2023

In the previous publication, the antioxidant capabilities of C60 and their derivatives were ascribed to the effectiveness of the C60 molecule, which can eliminate ROS through the C60's delocalized double bond system [75, 76]