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By binding with its steroidal ligands, dafachronic acids (DAs), DAF-12 induces reproductive development under favorable conditions such as an abundant food supply, whereas DAF-12 together with co-repressor DIN-1S promotes dauer diapause under harsh environmental conditions such as limited food and overcrowding 6,7

Statistics and reproducibility All experiments were repeated at least twice with independently prepared samples

Additionally, SELENOP expression was most robust in the choroid plexus and regions lining the brain ventricles (Sasuclark et al., 2019), which is in line with the previous studies (Rueli et al., 2015)