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Four reports addressed the effects of NAC in rodent models of opioid use disorder (Table 1)

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Wang S, Cao H, Zhao CC, Wang Q, Wang D, Liu J, et al

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Super-resolution microscopy revealed that GSH depletion caused bacterial chaining in the host cytosol, prohibiting proper actin-based motility and cell-to-cell spread

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Skaar, J

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Typical dosing ranges from 200-600 mg daily, starting at least three months before treatment

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