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Acta Med (Hradec Kralove) (2010) 53:737

Cell 148, 259272

Retrieved July 4, 2026

It was previously demonstrated that SOD1 can utilize H 2 O 2 as a sole substrate to produce hydroxyl radical 51,92,93 , a highly potent ROS that targets lipids, sugars, DNA bases, amino acids, and organic acids 38,94 , and against which no enzymatic defense exists