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Mitochondrial oxidative phosphorylation, essential for neuronal energy production, also generates reactive oxygen species (ROS), which increase with age and contribute to oxidative stress

Abstract Problems with sleep are one of the commonest reasons for seeking medical attention

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Figure 2 There are significant differences between molecular markers expressed by cells belonging to different subsets, which account for the different functions they perform (58, 68) ( Figure 2 )

Studies in senior dogs indicate an impairment of cell-mediated immunity, with reduced blood CD4 + T cells and a lower response of blood lymphocytes to stimulation by mitogens