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Both acrylamide and glycidamide bind to hemoglobin in red blood cells, and the determination of the resulting adducts provides an estimation of the internal dose that accounts for both absorption and metabolism of these compounds over the life of the red blood cells (120 days) (44)

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Mol Pharmacol 70:14691480 Kleer CG, Cao Q, Varambally S, Shen R, Ota I, Tomlins SA, Ghosh D, Sewalt RG, Otte AP, Hayes DF, Sabel MS, Livant D, Weiss SJ, Rubin MA, Chinnaiyan AM (2003) EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells