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To this purpose, the present review aims to discuss the advantages and challenges of using standard and cutting-edge techniques to discover salivary biomarkers which may be used in diagnosis/therapy of several chronic diseases with inflammatory consequences with the pursuit to possibly replace conventional paths with detectable soluble mediators in saliva

Conclusion In summary, NRF2, a key regulator of the cellular antioxidant stress response, is influenced by various PTMs and epigenetic modifications

Yet the deeper story of GHK-Cuits influence on gene expression, tissue remodeling, and regenerative signalingsuggests that we may only be beginning to understand the full potential of this small but biologically powerful peptide

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Figure 5 shows that there was no significant difference in the pooled effect size when any of the studies were excluded