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Pharmacokinetic oversimplification Popular descriptions frequently reduce these molecules to a single number MGF lasts minutes, LR3 lasts a day but the underlying pharmacology is more complicated

The oncometabolite 2-hydroxyglutarate produced by mutant IDH1 sensitizes cells to ferroptosis

Curcumin, a natural NF-B inhibitor, has been studied in the context of neurodegenerative and metabolic diseases, but its therapeutic value remains inconsistent owing to its poor bioavailability and rapid metabolism

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10.1111/j.1471-4159.2008.05668.x J