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Therefore, modulation of collagen proportions, particularly an increased collagen III/I ratio, has been shown to improve scar remodeling [67]

Over-expression of circadian clock gene Bmal1 affects proliferation and the canonical Wnt pathway in NIH-3T3 cells

BergmannOBhardwajRDBernardSZdunekSBarnabe-HeiderFWalshSet alEvidence for cardiomyocyte renewal in humans

This allows for the identification of novel compounds or combinations of drugs that are more effective in targeting cancer cells while minimizing the toxicity on healthy tissues [585, 626]