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The metabolite -linolenic acid from Lactobacillus plantarum triggers ferroptosis in CRC cells by damaging mitochondria [101]

High-risk individuals seeking prevention: Family history of AMD or glaucoma, high myopia increasing retinal detachment risk, diabetics with good glucose control wanting additional retinopathy prevention

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Zinc is not only involved in germ cell development and the synthesis of luteinizing hormone, follicle-stimulating hormone, and testosterone (99), but also serves as an essential component of various antioxidant enzymes, playing a key role in mitigating oxidative damage and improving sperm quality (100, 101)

The epigenetic regulatory roles of curcumin include the inhibition of DNA methyltransferases (DNMTs), regulation of histone modifications via the regulation of histone acetyltransferases (HATs) and histone deacetylases (HDACs), regulation of microRNAs (miRNA), action as a DNA binding agent and interaction with transcription factors