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Coauthored by a team of 13 researchersbasic scientists, translational researchers, and clinicians who see TB patientsthe study used multiple methods, including single-cell sequencing (which examines the genomes of individual cells) and flow cytometry (which analyzes individual cells as they flow past a series of lasers), as well as functional experiments with cells in vitro

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Using similar trajectory analyses, Karp and coworkers (2005) found that among novice smokers (mean age = 13 years), only one-fourth reported rapid escalation toward patterns of heavier use