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Description

We examine dysfunction across various conditions and analyze emerging therapeutic approaches targeting thermogenic activation and cellular senescence pathways, providing an integrated framework for understanding metabolic disease pathogenesis and identifying novel intervention strategies

Two millilitre fractions were collected and fractions containing TH were pooled and concentrated in an Amicon Ultra 15 ml filter with 100 kDa cutoff

GLOBOCAN-2022 recorded 324,398 new cases and 206,839 deaths worldwide, and demographic modelling predicts that annual incidence will exceed half a million by 2050, with the greatest absolute growth in Asia and the steepest percentage rise in sub-Saharan Africa [38]

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Criteria are used to identify a painful disk by provocation discography, including the type and location of pain and the appearance of the disk on an X-ray or computed tomography (CT) scan after the procedure