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urinaria extracts and demonstrated reduced HBeAg secretion in HepG2 2.2.15 cells post-treatment

Another source of toxicity of herbal medicines that is important to mention is adulteration of herbal products with undeclared pharmaceutical drugs and potentially toxic compounds such as harmful molecules present in other adulterating botanicals, pathogenic microorganisms, toxins, pesticides, agrochemical residues, and heavy metals (e.g., lead, mercury, and arsenic) (Saper et al., 2004

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Furthermore, AD and PD studies in mice found higher levels of antioxidant enzymes and a reduction of inflammatory markers in the brain, as well as improvement of behavioral impairment upon treatment with DMF (Table 1)