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They secrete pro-inflammatory mediators and elastase, which induce chondrocyte apoptosis and extracellular matrix (ECM) degradation, thereby promoting the progression of OA ( On one hand, similar to macrophages and other immune cells, neutrophils can secrete interleukin-1 (IL-1), which exacerbates cartilage damage in OA through multiple pathways

Venoarterial extracorporeal membrane oxygenation induces early immune alterations

GGT is an enzyme highly expressed in various tumor cells, which has been extensively employed as a marker for tumor tracking and therapy 23,26,27,28,29

1 The Vd is the parameter used to assess the amount of drug in the body from the measurement of a snapshot plasma concentration

the multi-gene approach is more comprehensive but more complex