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Proteomic analyses further suggest that gene expression changes related to oxidative stress (GPX1, superoxide dismutase 1), metabolism (ACACA, GAPDH), placentation (PGF, VEGF-A), and stem cell differentiation (POU5F1, SOX2) may underlie the observed improvement in embryo quality (Marinaro et al., 2018

But some side effects have been reported, including: Patients with a history of melanoma may be advised to avoid peptide therapy

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Loss of epithelial barrier integrity was accompanied by considerable ZZW-115-induced cell detachment as visualized by light microscopy (Fig