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Moreover, the tumor sizes in mice bearing EGR1-upregulated cells and treated with erastin were decreased compared with those in mice bearing parental cells and treated with erastin, which was reversed by the treatment of ZnPP (Figure 7A and B)

Furthermore, while ISO increased PRI, animals pretreated with TPN showed a decrease in PRI, enhancing oxygenation of the infarcted heart (Paulino et al., 2022)

Several issues remain unanswered, like the interaction between ROS and calcium signaling and the regulation of ROS during multiple environmental stresses