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In a small RCT where RIPC was performed using a pneumatic tourniquet place on both thighs for 10 minutes at the time of organ retrieval, no significant differences in eGFR or serum creatinine were described, while an increase in pro-inflammatory cytokines has been reported (134)

GSH alternates from its reduced form (GSH) to its oxidized glutathione disulfide form (GSSG), which turns back to GSH by glutathione reductase

Vavvas et al., 2018)

Its an accelerant, not a replacement

Beyond cosmetics, research has explored GHK-Cu's potential in therapeutic wound healing (chronic wounds, surgical recovery, diabetic ulcers), hair restoration, tissue engineering, nerve regeneration, lung disease, and even systemic anti-aging interventions