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It is essential to understand these mechanisms to develop effective treatment strategies

(2015) Antioxidant potential of hesperidin protects gentamicin induced nephrotoxicity in experimental rats

Taken together, these studies establish potentially converging disease mechanisms in ALS and spinal muscular atrophy, with ALS-causative mutants acquiring properties representing both gain (dysregulation of SMN) and loss (reduced RNA processing mediated by U1-snRNP) of function

The result showed that the purified GCLC undergoes succinylation modification with a gradually enhanced level following the increase of succinyl-CoA concentration (10100 M) (Fig

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