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3. Use twice daily for best results

146 Saadat S, Aslani MR, Ghorani V, et al

administered AAV serotype 8-mediated gene therapy, derived by cloning hABCB4 cDNA into a modified AAV expression cassette, as a single dose to ABCB4 knockout mice and found restoration of biliary phospholipid excretion with normalization of plasma alkaline phosphatase and bilirubin