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Mtb LeuC and LeuD form a heterodimer to exert enzymatic activity in catalysis of the stereospecific conversion from -isopropylmalate to -isopropylmalate, requiring an iron-sulfur cluster ([4Fe-4S]) in its catalytic center [228]

A., Svoboda, M

The P53 operates as a pivotal element in safeguarding cells against malignant transformation and atypical proliferation [40, 41]

Model building, refinement, and structure analysis All atomic models were built using Coot (v0.9.8.7) 86 and ChimeraX (v1.9) 87 followed by several rounds of rigid-body, real-space, and B-factor refinement using phenix.real_space_refinement in Phenix (v1.21) 88