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2021;10:e64188 Liu H

[DOI] [PubMed] [Google Scholar] 61.Chen C., Garcia-Santos D., Ishikawa Y., Seguin A., Li L., Fegan K.H., Hildick-Smith G.J., Shah D.I., Cooney J.D., Chen W., et al

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Traditional antifolate chemotherapeutics have many deleterious side effects due to the importance of folate pathways in healthy proliferating cells and Table 1: Established anti-folate antineoplastic agents (Newman A C and Maddocks O D K, 2017) One-carbon metabolism plays a significant role in References: Kalhan S C