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One study identified increased expression of four genes related to ethanol tolerance (HSP104, PRO1, TPS1, and SOD1) in ethanol-tolerant strains of S

53 , rho 0 mutant cells without respiratory competence displayed lower intracellular ROS accumulation and higher resistance to Pb than the wt strain

Interestingly, a null variant is encountered for two members, GSTT1 and GSTM1 , whereby the entire gene is homozygously deleted in a considerable proportion of different populations, resulting in the complete absence of the corresponding enzyme activity 7,8

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