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The peptide has been studied for various applications related to aging, cellular regeneration, and longevity research

The C5 domain of nocardicin NRPS (NocB) not only fulfills its canonical function by forming the corresponding amide bond in the growing peptide chain, but also mediates cyclization of the beta lactam ring 29

Controlled study of induced granulomas treated with NAC showed 2-fold increase in GSH, 3-fold increase in Interferon-, 2- and 3-fold reduction in tumor necrosis factor- (TNF-) at 8 and 15 days, reduced reactive oxygen ions and reduced necrosis as compared to controls (68)

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Both RAW 264.7 cells and peritoneal macrophages were maintained in RPMI 1640 medium supplemented with 10% fetal bovine serum, 5% CO, and 95% air at 37C