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Chronic joint pain Persistent joint issues that haven't fully resolved with physical therapy, rest, or standard anti-inflammatory treatment

Frontiers in Pharmacology, 11 , Article 608518

Stanley et al

The studies began with the determination of the optimal dosing for Cagrilintide in both chow-fed and high-fat diet (HFD)-fed wild-type (WT) mice, followed by analyses of its receptor dependence using receptor activity-modifying protein (RAMP) knockout (KO) models, and mechanistic studies involving neuronal activation and gene expression profiling [2]