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In other patients, the dose may not yet be optimized, or side effects may prevent adequate titration

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53 They not only revealed a critical, albeit complex, role of claudin-2 in intestinal homeostasis, regulating epithelial permeability, inflammation, and proliferation but also suggested a potential adaptive function for the increased claudin-2 expression in IBD patients

Identification of competitive inhibitors of the human taurine transporter TauT in a human kidney cell line