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LD: Data curation, Investigation, Writing original draft

Recurrent and secondary infection Infection recurrence was observed in 99 out of 2,070 patients in the PCT group and in 75 out of 2,080 patients in the SOC group, indicating a significant difference (OR 1.36, 95% CI: 1.10, 1.68, p = 0.008) (Fig

In conclusion, addressing the challenges and exploring future directions in harnessing microbial-derived metabolites for cancer immunity, immunotherapy, and chemotherapy requires interdisciplinary collaboration, technological innovation, and a deep commitment to advancing our understanding of the intricate relationships between the microbiome and cancer