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That difference is important because it reframes expectations and treatment goals

The 176-191 fragment without the tyrosine addition is the unmodified native sequence

A head-to-head comparison with minoxidil would be valuable for clinical decision-making

This condition is known as GH deficiency (GHD) but in analogy with other pituitary deficiencies leading to peripheral hormone deficiencies the term secondary IGF-I deficiency was proposed (Rosenfeld et al)