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Identification of drought, cadmium and root-lesion nematode infection stress-responsive transcription factors in ramie

Fuhrmann found that the content of NCOA4 in macrophages decreased under hypoxic conditions, increasing intracellular ferritin content, and thereby enhancing macrophage resistance to ferroptosis [69]

In particular, since the M105 residue resides within a TPR module, the M105I substitution implies an accommodation of the I105 (hydrophobic residue)

Concomitantly, water influx causes matrix swelling, rupture of the rigid OMM and release of apoptogenic proteins sequestered in IMS although, apoptotic cell death under MPT is inhibited due to energetic failure and ATP exhaustion and oxidative stress-mediated caspase inactivation

doi: 10.3389/fimmu.2018.00339 198 MorrisD.KhurasanyM.NguyenT.KimJ.GuilfordF.MehtaR.et al