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Abstract Rampant phospholipid peroxidation initiated by iron causes ferroptosis unless this is restrained by cellular defences

This damages the cell and mitochondrial membranes, and ultimately causing cell death (172)

REICK2, EF501 vs

4.1 Sex dimorphism in lipid metabolism and its impact on ferroptosis substrates For a long time, low-density lipoprotein cholesterol (LDL-C) has been considered a core risk factor for AS